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\n \n <\/p>\n

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\n \n <\/p>\n

\n \u6d3b\u7ec6\u80de\u4ea7\u54c1\u7684\u751f\u4ea7\u4ea4\u4ed8\u662f\u4e00\u9879\u590d\u6742\u7684\u6d3b\u52a8\uff0c\u4e00\u662f\u539f\u6750\u6599\u4eba\u4f53\u5316\uff0c\u610f\u5473\u7740\u539f\u6750\u6599\u96be\u4ee5\u6807\u51c6\u5316\uff1b\u4e8c\u662f\u8fc7\u7a0b\u4e2a\u4f53\u5316\uff0c\u4e0d\u540c\u6765\u6e90\u7684\u539f\u6750\u6599\u8981\u5b9e\u73b0\u540c\u6837\u7684\u8d28\u91cf\u76ee\u6807\uff0c\u751f\u4ea7\u8fc7\u7a0b\u96be\u4ee5\u5b8c\u5168\u7edf\u4e00\uff0c\u4e0d\u4ec5\u6d89\u53ca\u5de5\u827a\u8fd8\u6d89\u53ca\u60a3\u8005\u75c5\u60c5\u7684\u5b9e\u65f6\u8fdb\u5c55\u60c5\u51b5\uff1b\u4e09\u662f\u7ec8\u4ea7\u54c1\u7684\u6d3b\u6027\u5316\uff0c\u8868\u660e\u4ea7\u54c1\u7684\u7ec8\u4ea7\u54c1\u8d28\u91cf\u7684\u7a33\u5b9a\u6027\u6781\u6613\u53d7\u5230\u6e29\u5ea6\u3001\u65f6\u95f4\u4ee5\u53ca\u50a8\u5b58\u8fd0\u8f93\u6761\u4ef6\u7b49\u5916\u5728\u56e0\u7d20\u7684\u5f71\u54cd\u3002\u56e0\u6b64\uff0cCGT\u4ea7\u54c1\u5176\u5b9e\u5c31\u662f\u8fc7\u7a0b\u63a7\u5236\u3002\u6b63\u56e0\u4e3a\u5982\u6b64\uff0c\u8fc7\u53bb\u751f\u7269\u533b\u836f\u884c\u4e1a\u884c\u4e4b\u6709\u6548\u7684\u751f\u4ea7\u65b9\u5f0f\u65e0\u6cd5\u6ee1\u8db3\u6d3b\u7ec6\u80de\u5546\u4e1a\u5316\u53d1\u5c55\u9700\u6c42\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u4e8c\u3001\u6d3b\u7ec6\u80de\u4ea7\u54c1\u5927\u89c4\u6a21\u751f\u4ea7\u7684\u884c\u4e1a\u6311\u6218\u4e0e\u8d5b\u52a8\u65b9\u6848<\/span><\/strong>\n <\/p>\n

\n \n <\/p>\n

\n \u5f53\u524d\uff0cCGT\u7684\u7814\u7a76\u70ed\u6f6e\u4e0e\u5148\u8fdb\u7684\u673a\u5668\u5b66\u4e60\u548c\u81ea\u52a8\u5316\u7684\u5e7f\u6cdb\u5e94\u7528\u4e0d\u8c0b\u800c\u5408\u3002CGT\u9776\u70b9\u63a2\u7d22\u65f6\uff0c\u5df2\u5c06\u81ea\u52a8\u5316\u673a\u5668\u5b66\u4e60\u7528\u4e8e\u7814\u7a76\u5f00\u53d1\u3002\u4f46\u8981\u5b9e\u73b0\u81ea\u52a8\u6536\u96c6\u548c\u5206\u6790\u6297\u539f\u6570\u636e\uff0c\u53d1\u73b0\u6709\u4ef7\u503c\u7684\u76ee\u6807\u9776\u70b9\uff0c\u7834\u8bd1\u57fa\u56e0\u5e8f\u5217\u4fe1\u606f\uff0c\u786e\u8ba4\u5019\u9009\u6297\u539f\uff0c\u5b9e\u73b0\u751f\u4ea7\u5de5\u827a\u7684\u8fed\u4ee3\uff0c\u8fd8\u9700\u8981\u66f4\u591a\u7684\u57fa\u4e8e\u884c\u4e1a\u7406\u89e3\u57fa\u7840\u4e0a\u7684\u6280\u672f\u7a81\u7834\u3002\u4e00\u76f4\u4ee5\u6765\uff0c\u7814\u7a76\u8005\u90fd\u81f4\u529b\u4e8e\u627e\u5230\u53ef\u4ee5\u51c6\u786e\u5b9a\u4e49\u6d3b\u7ec6\u80de\u57f9\u517b\u8fc7\u7a0b\u4e2d\u7684\u8d28\u91cf\u53c2\u6570\uff0c\u5e76\u80fd\u5c06\u5176\u4e0e\u751f\u7269\u5b66\u529f\u80fd\u4ee5\u53ca\u4e34\u5e8a\u6cbb\u7597\u6548\u679c\u8fdb\u884c\u5173\u8054\u3002\u56e0\u6b64\uff0c\u5927\u89c4\u6a21\u5730\u751f\u4ea7\u3001\u83b7\u5f97\u8d28\u91cf\u7a33\u5b9a\u3001\u80fd\u5b9e\u73b0\u4e34\u5e8a\u6cbb\u7597\u6548\u679c\u7684\u7ec6\u80de\u4ea7\u54c1\u662f\u4e00\u9879\u6301\u7eed\u6027\u6311\u6218\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u8d5b\u52a8\u667a\u9020\u81f4\u529b\u4e8e\u5c06\u7ec6\u80de\u5206\u6790\u6570\u636e\u3001\u9ad8\u901a\u91cf\u7684\u751f\u7269\u4fe1\u606f\u5206\u6790\u548c\u673a\u5668\u5b66\u4e60\u8fdb\u884c\u6574\u5408\u3002\u968f\u7740\u65f6\u95f4\u7684\u63a8\u79fb\uff0c\u6211\u4eec\u7684\u76ee\u6807\u662f\u81ea\u52a8\u91c7\u96c6\u548c\u5904\u7406CGT\u7597\u6cd5\u57f9\u517b\u8fc7\u7a0b\u4e2d\u7684\u8868\u8fbe\u8c31\u3001\u8f6c\u5f55\u7ec4\u3001\u86cb\u767d\u8d28\u7ec4\u548c\u4ee3\u8c22\u7ec4\u6570\u636e\uff0c\u4ece\u800c\u5c06\u8fd9\u4e9b\u4fe1\u606f\u4e0e\u7ec6\u80de\u89c2\u5bdf\u3001\u751f\u4ea7\u8fc7\u7a0b\u7d27\u5bc6\u8054\u7cfb\u8d77\u6765\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u9996\u5148\uff0c\u4f9b\u5e94\u94fe\u7f29\u77ed\u5e26\u6765\u7684\u65f6\u95f4\u4e0e\u6210\u672c\u7684\u538b\u7f29\u3002\u7ec6\u80de\u836f\u7269\u516c\u53f8\u5317\u79d1\u751f\u7269\u91c7\u7528\u8d5b\u52a8\u667a\u9020\u7684\u6570\u667a\u5316\u4ea7\u7ebf\u65b9\u6848\u5728\u54c8\u5c14\u6ee8\u843d\u5730\u90e8\u7f72\uff0c\u7528\u4e8e\u751f\u4ea7\u4e2a\u4f53\u5316\u6cbb\u7597\u4ea7\u54c1rFib\u2464\uff0c\u6ee1\u8db3\u5728\u5f53\u5730\u5f00\u5c55\u7684\u4e34\u5e8a\u7814\u7a76\u9700\u6c42\u3002\u5c31\u8fd1\u90e8\u7f72\u751f\u4ea7\u8bbe\u65bd\uff0c\u7528\u4e8e\u751f\u4ea7\u7684\u539f\u6750\u6599\uff08\u60a3\u8005\u76ae\u80a4\u7ec4\u7ec7\uff09\u4e0d\u9700\u8981\u957f\u8ddd\u79bb\u8fd0\u8f93\u5230\u4f4d\u4e8e\u6df1\u5733\u7684\u5236\u5907\u4e2d\u5fc3\uff0c\u8282\u7701\u539f\u6750\u6599\u548c\u7ec8\u4ea7\u54c1\u53cc\u5411\u8fd0\u8f93\u6240\u9700\u65f6\u95f4\u5468\u671f\u4e0e\u7ecf\u6d4e\u6210\u672c\uff0c\u4e5f\u8c41\u514d\u4e86\u957f\u8ddd\u79bb\u8fd0\u8f93\u8fc7\u7a0b\u4e2d\u8d28\u91cf\u63a7\u5236\u7684\u4e0d\u786e\u5b9a\u6027\u3002\u540c\u65f6\uff0c\u8bb8\u591a\u52b3\u52a8\u5bc6\u96c6\u7684\u64cd\u4f5c\u6b65\u9aa4\u7ecf\u7531\u673a\u68b0\u81ea\u52a8\u5316\u7684\u66ff\u4ee3\uff0c\u66f4\u8282\u7701\u4e86\u52b3\u52a8\u529b\u6210\u672c\uff0c\u540c\u65f6\u5927\u5927\u51cf\u5c11\u4e86\u4eba\u5de5\u53c2\u4e0e\u751f\u4ea7\u8fc7\u7a0b\u5bf9\u9ad8\u6d01\u51c0\u7ea7\u522b\u7a7a\u95f4\u7684\u9700\u6c42\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u5176\u6b21\uff0c\u6a21\u5757\u64cd\u4f5c\u6570\u667a\u5316\u4ea7\u7ebf\u5177\u6709\u66f4\u4f18\u7684\u6210\u672c\u6548\u7387\u4f18\u52bf\u3002\u5728\u4e2a\u4f53\u5316\u4ea7\u54c1\u7684\u751f\u4ea7\u8fc7\u7a0b\u4e2d\uff0c\u8bbe\u5907\u53d1\u6325\u7740\u91cd\u8981\u7684\u4f5c\u7528\u3002\u751f\u4ea7\u81ea\u52a8\u5316\u65e2\u53ef\u91c7\u53d6\u57fa\u4e8e\u6a21\u5757\u64cd\u4f5c\u7684\u6570\u667a\u5316\u4ea7\u7ebf\uff0c\u5c06\u751f\u4ea7\u8fc7\u7a0b\u5206\u89e3\u4e3a\u591a\u4e2a\u4e0d\u540c\u7684\u6b65\u9aa4\u4ee5\u63a7\u5236\u7cfb\u7edf\u5b9e\u73b0\u751f\u4ea7\u7684\u8fde\u7eed\u6027\u4e0e\u81ea\u52a8\u5316\uff1b\u4e5f\u53ef\u91c7\u7528\u96c6\u6210\u5f0f\u81ea\u52a8\u5316\u65b9\u6848\uff0c\u5c06\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u7684\u8bb8\u591a\u4e0d\u540c\u7684\u6b65\u9aa4\u7b80\u5316\u4e3a\u4e00\u4e2a\u5355\u4e00\u7684\u81ea\u52a8\u5316\u5e73\u53f0\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u4f46\u5bf9\u4e8e\u4e2a\u4f53\u5316CGT\u4ea7\u54c1\u6765\u8bb2\uff0c\u5176\u751f\u4ea7\u5de5\u827a\u7684\u5468\u671f\u8f83\u957f\uff0c\u5e73\u5747\u90fd\u9700\u898120\u591a\u5929\u7684\u751f\u4ea7\u5468\u671f\uff0c\u96c6\u6210\u5f0f\u81ea\u52a8\u5316\u610f\u5473\u7740\u5bf9\u8bbe\u5907\u7684\u5360\u7528\u65f6\u95f4\u8f83\u957f\uff0c\u65e0\u6cd5\u5b9e\u73b0\u591a\u6837\u672c\u5e76\u884c\u5904\u7406\u7684\u89c4\u6a21\u5316\u4f18\u52bf\uff0c\u53cd\u800c\u662f\u6a21\u5757\u64cd\u4f5c\u7684\u6570\u667a\u5316\u65b9\u6848\u66f4\u5177\u6709\u6210\u672c\u6548\u7387\u4f18\u52bf\uff0c\u4e14\u80fd\u5b9e\u73b0\u4e0d\u540c\u6837\u672c\u8fde\u7eed\u751f\u4ea7\u548c\u591a\u6837\u672c\u5e76\u884c\u5904\u7406\u7684\u201c\u6d41\u6c34\u7ebf\u201d\u4f18\u52bf\u3002\u672c\u9879\u76ee\u91c7\u7528\u7684\u662f\u7ec6\u80de\u4ea7\u4e1a\u56fd\u5bb6\u5de5\u7a0b\u4e2d\u5fc3\u7814\u7a76\u6210\u679c\u6a21\u5757\u64cd\u4f5c\u7684\u6570\u667a\u5316\u4ea7\u7ebf\u3002\u901a\u8fc7\u751f\u7269\u6280\u672f\uff08BT\uff09+\u4fe1\u606f\u6280\u672f\uff08IT\uff09+\u81ea\u52a8\u5316\u6280\u672f\uff08AT\uff09\u7684\u878d\u5408\uff0c\u91c7\u7528\u81ea\u4e3b\u7814\u53d1\u7684\u81ea\u52a8\u5316\u63a7\u5236\u7cfb\u7edf\u548c\u5168\u5bc6\u95ed\u3001\u4e00\u6b21\u6027\u6280\u672f\uff0c\u5efa\u8bbe\u4e86\u7b26\u5408GMP\u2465\u8981\u6c42\u7684\u5168\u6d41\u7a0b\u81ea\u52a8\u5316\u3001\u5c01\u95ed\u5f0f\u3001\u8fde\u7eed\u6027\u3001\u6a21\u5757\u5316\u7ec6\u80de\u5236\u5242\u4ea7\u7ebf\uff0c\u5b9e\u73b0\u6a21\u5757\u64cd\u4f5c\u7684\u81ea\u52a8\u5316\u751f\u4ea7\uff0c\u89e3\u51b3\u4e86\u4eba\u5de5\u4ea7\u7ebf\u5efa\u8bbe\u5468\u671f\u957f\u548c\u6d01\u51c0\u8f66\u95f4\u9700\u6c42\u5927\u3001\u8d28\u91cf\u4e0d\u5747\u4e00\u3001\u5236\u5907\u5de5\u7a0b\u5e08\u4f9b\u7ed9\u4e0d\u8db3\u4ee5\u53ca\u751f\u4ea7\u8fc7\u7a0b\u4e0d\u900f\u660e\u7684\u4ea7\u4e1a\u53d1\u5c55\u96be\u9898\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u4ea7\u7ebf\u5305\u62ec5\u4e2a\u53ef\u652f\u6491\u6027\u7684\u529f\u80fd\u6a21\u5757\uff1a\u5168\u81ea\u52a8\u7ec6\u80de\u5904\u7406\u7cfb\u7edf\u3001\u667a\u80fd\u914d\u6db2\u7cfb\u7edf<\/span>\u3001\u77e9\u9635\u5f0f\u57f9\u517b\u7cfb\u7edf\u3001\u667a\u80fd\u5206\u88c5\u7cfb\u7edf\u3001\u7ec6\u80de\u5168\u751f\u547d\u5468\u671f\u7ba1\u7406\u7cfb\u7edf\u3002\u901a\u8fc7\u7ec6\u80de\u4ea7\u4e1a\u56fd\u5bb6\u5de5\u7a0b\u4e2d\u5fc3\u7684\u901a\u4fe1\u534f\u8bae\u63a7\u5236\u8fde\u63a5\u4e0d\u540c\u7684\u529f\u80fd\u6a21\u5757\u642d\u5efa\u80fd\u5b9e\u65bd\u8fde\u7eed\u751f\u4ea7\u7684\u81ea\u52a8\u5316\u4ea7\u7ebf\u3002\u91c7\u7528\u6570\u667a\u6280\u672f\u7a81\u7834\u667a\u80fd\u6392\u4ea7\u3001\u591a\u6279\u6b21\u5e76\u884c\u3001\u591a\u5de5\u827a\u517c\u5bb9\u7b49\u6280\u672f\u74f6\u9888\uff0c\u5b8c\u6210\u7ec6\u80de\u6d17\u6da4\u3001\u5206\u9009\u6d53\u7f29\u3001\u6eb6\u6db2\u7f6e\u6362\u3001\u57f9\u517b\u3001\u6536\u83b7\u3001\u5236\u5242\u914d\u65b9\u7b49\u7ec6\u80de\u5236\u5242\u5168\u6d41\u7a0b\u7684\u65e0\u4eba\u5316\u751f\u4ea7\uff0c\u5b9e\u73b0\u8fc7\u7a0b\u53ef\u89c6\uff0c\u5de5\u827a\u81ea\u4e3b\u6267\u884c\uff0c\u5e76\u6ee1\u8db3\u76d1\u7ba1\u8981\u6c42\u7684\u6570\u636e\u5b9e\u65f6\u6536\u96c6\u548c\u5168\u751f\u547d\u5468\u671f\u8ffd\u6eaf\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u96c6\u4e2d\u5f0f\u751f\u4ea7\u548c\u533a\u57df\u5206\u5e03\u5f0f\u751f\u4ea7\u7ebf\u7684\u6210\u672c\u6548\u7387\u6bd4\u8f83\u5206\u6790\u3002\u90e8\u7f72\u5b8c\u6210\u540e\uff0c\u6211\u4eec\u5229\u7528\u771f\u5b9e\u4e16\u754c\u7684\u751f\u4ea7\u6570\u636e\u8fdb\u884c\u6210\u672c\u63a8\u5bfc\uff0c\u5206\u6790\u6bd4\u8f83\u4e86\u5206\u5e03\u5f0f\u7684\u201c\u5e8a\u8fb9\u201d\u6570\u667a\u5316\u751f\u4ea7\u6a21\u5f0f\u4e0e\u4eba\u5de5\u96c6\u4e2d\u751f\u4ea7\u6a21\u5f0f\u7684\u6210\u672c\u6548\u7387\uff0c\u770b\u770b\u54ea\u79cd\u6a21\u5f0f\u66f4\u5177\u6210\u672c\u4e0e\u6548\u7387\u4f18\u52bf\uff0c\u52a0\u5feb\u521b\u65b0\u7597\u6cd5\u7684\u4e34\u5e8a\u8f6c\u5316\uff0c\u4fc3\u8fdb\u65b0\u4ea7\u54c1\u3001\u65b0\u670d\u52a1\u4e0e\u65b0\u4e1a\u6001\u7684\u53d1\u5c55\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n rFib\u7684\u751f\u4ea7\u8fc7\u7a0b\u5305\u62ec\u76ae\u80a4\u7ec4\u7ec7\u91c7\u96c6\uff0c\u5206\u79bb\u5904\u7406\uff0c\u8bf1\u5bfc\u8f6c\u67d3\uff0c\u57f9\u517b\u6269\u589e\uff0c\u6d17\u6da4\u6536\u83b7\uff0c\u51bb\u5b58\u3002\u90e8\u7f72\u7684\u6570\u667a\u5316\u751f\u4ea7\u7ebf\u53ef\u5728\u4e00\u6b21\u6027\u7684\u5bc6\u95ed\u7ba1\u8def\u7cfb\u7edf\u4e2d\u5b8c\u6210\u4ece\u8bf1\u5bfc\u5230\u6536\u83b7\u3001\u914d\u65b9\u5316\u7684\u64cd\u4f5c\u6b65\u9aa4\uff0c\u8282\u7701\u751f\u4ea7\u4eba\u529b\u3001\u7a7a\u95f4\u548c\u65f6\u95f4\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u64cd\u4f5c\u4eba\u5458\uff1a\u201c\u5e8a\u8fb9\u201d\u6570\u667a\u5316\u751f\u4ea7\u7ebf\u914d\u7f6e2\u540d\u64cd\u4f5c\u4eba\u5458\uff0c\u89c2\u5bdf\u751f\u4ea7\u7ebf\u63a7\u5236\u5927\u5c4f\u548c\u8f85\u52a9\u751f\u4ea7\u64cd\u4f5c\uff08\u5bc6\u95ed\u7ba1\u8def\u5b89\u88c5\u7b49\uff09\u3002\u6df1\u5733\u4eba\u5de5\u751f\u4ea7\u7ebf\u914d\u7f6e\u4e8623\u540d\u4e13\u4e1a\u5de5\u7a0b\u5e08\u53c2\u4e0e\u4f5c\u4e1a\u751f\u4ea7\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u6210\u672c\u786e\u8ba4\u548c\u6838\u7b97\u3002\u7b2c\u4e00\uff0c\u786e\u8ba4\u81ea\u52a8\u5316\u751f\u4ea7\u7ebf\u5305\u62ec\u7ec6\u80de\u8f6c\u67d3\u3001\u57f9\u517b\u6269\u589e\u3001\u6d17\u6da4\u6536\u83b7\u3001\u914d\u65b9\u5316\u5206\u88c5\uff0c\u4ee5\u53ca\u5bf9\u5e94\u4eba\u5de5\u64cd\u4f5c\u7684\u6b65\u9aa4\u548c\u6240\u9700\u5de5\u65f6\u3002\u7b2c\u4e8c\uff0c\u786e\u5b9a\u603b\u4f53\u751f\u4ea7\u8fc7\u7a0b\u7684\u56fa\u5b9a\u6210\u672c\u548c\u53d8\u52a8\u6210\u672c<\/span>\uff0c\u56fa\u5b9a\u6210\u672c\u5305\u62ec\u8bbe\u65bd\u5efa\u8bbe\u3001\u5382\u623f\u88c5\u4fee\u3001\u8bbe\u5907\/\u4ea7\u7ebf\u8d2d\u7f6e\u3001\u4eba\u5458\u652f\u51fa\uff08\u85aa\u916c\u548c\u57f9\u8bad\u8d39\u7528\uff09\uff1b\u53d8\u52a8\u6210\u672c\u4e3b\u8981\u5305\u62ec\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u8bd5\u5242\/\u8017\u6750\u7684\u6d88\u8017\u652f\u51fa\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u901a\u8fc7\u5206\u6790rFib\u6570\u667a\u5316\u4ea7\u7ebf\u4e0e\u6df1\u5733\u4eba\u5de5\u4ea7\u7ebf\u7684\u5efa\u8bbe\u5468\u671f\u3001\u8bd5\u8fd0\u884c\u6d4b\u8bd5\uff0c\u5206\u5e03\u5f0f\u6570\u667a\u5316\u4ea7\u7ebf\u7684\u4f18\u52bf\u5728\u4e8e\uff0c\u4f9b\u5e94\u94fe\u73af\u8282\u51cf\u5c11\uff0c\u7701\u7565\u4e86\u751f\u4ea7\u539f\u6750\u6599\u91c7\u96c6\u540e\u4ee5\u53ca\u7ec8\u4ea7\u54c1\u7684\u957f\u8ddd\u79bb\u8fd0\u8f93\uff0c\u5305\u62ec\u4e34\u5e8a\u4e2d\u5fc3\u5230\u96c6\u4e2d\u751f\u4ea7\u8bbe\u65bd\u53cc\u5411\u8fd0\u8f93\u7684\u65f6\u95f4\u3001\u6210\u672c\u4ee5\u53ca\u8d28\u63a7\u7684\u4e0d\u786e\u5b9a\u6027\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u751f\u4ea7\u8fc7\u7a0b\u4e2d\u7684\u52b3\u52a8\u529b\u7684\u7cbe\u7b80\uff0c\u6570\u91cf\u4e0a\u4ece23\u540d\u51cf\u52302\u540d\uff0c\u4e13\u4e1a\u6280\u80fd\u4e0a\u4ece\u7ec6\u80de\u5236\u5907\u5de5\u7a0b\u5e08\u5230\u751f\u4ea7\u7ebf\u64cd\u4f5c\u4eba\u5458\uff0c\u6d01\u51c0\u5382\u623f\u7684\u9762\u79ef\u75311800\u5e73\u65b9\u7c73B\u7ea7\u6d01\u51c0\u7a7a\u95f4\u5230142\u5e73\u65b9\u7c73\u7684D\u7ea7\u6d01\u51c0\u7a7a\u95f4\uff1b\u540c\u65f6\uff0c\u76f8\u8f83\u4eba\u5de5\u751f\u4ea7\u7ebf\uff0c\u6570\u667a\u5316\u751f\u4ea7\u7ebf\u5177\u5907\u591a\u60a3\u8005\u6837\u672c\u5e76\u884c\u751f\u4ea7\u5904\u7406\u7684\u201c\u6d41\u6c34\u7ebf\u201d\u4f18\u52bf\uff0c\u80fd\u5728\u6700\u5927\u4ea7\u80fd\u8fd0\u884c\u7684\u72b6\u6001\u4e0b\u8fdb\u4e00\u6b65\u83b7\u5f97\u6210\u672c\u4f18\u52bf\uff0c\u800c\u4eba\u5de5\u751f\u4ea7\u7ebf\u5219\u4e0d\u5177\u5907\u76f8\u5e94\u591a\u6837\u672c\u5e76\u884c\u5904\u7406\u7684\u53ef\u6269\u5c55\u6027\uff0c\u66f4\u591a\u7684\u6837\u672c\u751f\u4ea7\u610f\u5473\u7740\u9700\u8981\u66f4\u591a\u7684B\u7ea7\u6d01\u51c0\u623f\u95f4\u548c\u64cd\u4f5c\u5de5\u7a0b\u5e08\uff0c\u4e5f\u610f\u5473\u7740\u56fa\u5b9a\u6210\u672c\u6210\u6bd4\u4f8b\u7684\u6500\u5347\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u867d\u7136\uff0c\u6b64\u5206\u5e03\u5f0f\u6570\u667a\u5316\u751f\u4ea7\u7ebf\u662f\u7528\u4e8e\u751f\u4ea7rFib\u7597\u6cd5\u7684\u751f\u4ea7\uff0c\u4f46rFib\u7597\u6cd5\u4e0eCAR-T\u548cTILs\u7597\u6cd5\u5177\u6709\u7c7b\u4f3c\u6027\uff1a\u540c\u6837\u662f\u5355\u4eba\u5355\u4efd\u751f\u4ea7\uff0c\u9700\u8981\u5373\u65f6\u91c7\u96c6\u60a3\u8005\u7684\u7ec4\u7ec7\u6837\u672c\u4f5c\u4e3a\u751f\u4ea7\u539f\u6750\u6599\uff0c\u7ecf\u7531\u957f\u8ddd\u79bb\u8fd0\u8f93\u5230\u751f\u4ea7\u4e2d\u5fc3\u6216\u5c31\u5730\u5f00\u59cb\u751f\u4ea7\uff0c\u7ecf\u8fc7\u8d28\u68c0\uff0c\u5408\u683c\u653e\u884c\uff0c\u7136\u540e\u7ecf\u7531\u957f\u8ddd\u79bb\u8fd0\u8f93\u914d\u9001\u6216\u5c31\u8fd1\u7ed9\u60a3\u8005\u56de\u8f93\u6cbb\u7597\u3002\u56e0\u6b64\uff0c\u7ec6\u80de\u4ea7\u4e1a\u56fd\u5bb6\u5de5\u7a0b\u4e2d\u5fc3\u90e8\u7f72\u7684\u201c\u5e8a\u8fb9\u201d\u57fa\u4e8e\u6a21\u5757\u64cd\u4f5c\u7684\u6570\u667a\u5316\u4ea7\u7ebf\u5bf9\u4e2a\u4f53\u5316CAR-T\u6cbb\u7597\u548cTILs\u7597\u6cd5\u7b49CGT\u7684\u4ea7\u7ebf\u90e8\u7f72\u9009\u62e9\u5177\u6709\u8f83\u5f3a\u7684\u53ef\u53c2\u7167\u6027\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u4e09\u3001\u6570\u667a\u6280\u672f\u4fc3\u8fdbCGT\u751f\u4ea7\u521b\u65b0<\/span><\/strong>\n <\/p>\n

\n \n <\/p>\n

\n \u4e34\u5e8a\u533b\u7597\u8fdb\u5165\u4e86\u4e2a\u4f53\u5316\u7cbe\u51c6\u533b\u7597\u53d1\u5c55\u9636\u6bb5\uff0c\u5f53\u524d\u533b\u836f\u4ea7\u4e1a\u4e2d\u5927\u884c\u5176\u9053\u7684\u751f\u4ea7\u89c4\u6a21\u6548\u5e94\u5728\u4ee5\u4e2a\u4f53\u5316\u6216\u5c0f\u7fa4\u4f53\u4e3a\u57fa\u672c\u7279\u5f81\u7684CGT\u9886\u57df\u5931\u53bb\u4e86\u5e94\u7528\u573a\u666f\u3002\u56e0\u6b64\uff0c\u80fd\u9002\u5e94\u5c0f\u6279\u91cf\u3001\u591a\u6279\u6b21\u3001\u66f4\u9ad8\u8d28\u91cf\u4e0e\u52a8\u6001\u76d1\u6d4b\u8981\u6c42\u7684\u667a\u80fd\u751f\u4ea7\u521b\u65b0\u975e\u5e38\u8feb\u5207\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u800c\u201c\u6d3b\u201d\u7684CGT\u4ea7\u54c1\u8981\u91cd\u590d\u8fc7\u53bb\u5236\u836f\u5de5\u4e1a\u4e2d\u7684\u201c\u91cd\u78c5\u70b8\u5f39\u201d\u6548\u5e94\uff0c\u5fc5\u987b\u4ee5\u65b0\u7684\u601d\u8def\u548c\u89c6\u89d2\u5e94\u5bf9\u6a2a\u4e98\u5728\u8def\u4e0a\u7684\u751f\u4ea7\u6311\u6218\uff0c\u4ee5\u6570\u5b57\u5316\u3001\u81ea\u52a8\u5316\u3001\u5728\u7ebf\u5b9e\u65f6\u7684\u667a\u80fd\u3001\u67d4\u6027\u751f\u4ea7\u7ebf\u642d\u5efa\u5982\u82af\u7247\u4ea7\u4e1a\u4e00\u6837\u7684\u5feb\u901f\u3001\u54cd\u5e94\u6027\u7684\u4ea4\u4ed8\u4f53\u7cfb\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

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\n \n <\/p>\n

\n \u751a\u81f3\u662f\u4f01\u4e1a\u7684\u9ad8\u7ba1\u4e5f\u5e76\u4e0d\u8ba4\u4e3a\uff0c\u4e0e\u7ba1\u7ebf\u521b\u65b0\u914d\u5957\u7684\u751f\u4ea7\u667a\u80fd\u5316\u521b\u65b0\u662f\u836f\u5382\u5fc5\u4e0d\u53ef\u5c11\u7684\u201c\u6218\u7565\u80fd\u529b\u201d\u4e0e\u201c\u6838\u5fc3\u4f18\u52bf\u201d\u3002\u56e0\u6b64\u4e5f\u65e0\u6cd5\u8ba4\u8bc6\u5230\uff0c\u5f53\u524d\u4f4e\u6548\u7684\u4eba\u5de5\u751f\u4ea7\u3001\u9759\u6001\u7684\u4e8b\u540e\u7ea0\u9519\uff08\u751f\u4ea7\uff09\u6a21\u5f0f\u80cc\u540e\u9ad8\u6602\u7684\u8fd0\u8425\u6210\u672c\u548c\u8d28\u91cf\u6210\u672c\uff0c\u4ee5\u53ca\u60a3\u8005\u7b49\u5f85\u6cbb\u7597\u7684\u673a\u4f1a\u6210\u672c\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

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\n \n <\/p>\n

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\n \n <\/p>\n

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\n \n <\/p>\n

\n \u5728\u751f\u7269\u533b\u836f\u751f\u4ea7\u4e2d\uff0c\u666e\u904d\u5b58\u5728\u4e00\u4e2a\u201c\u5171\u8bc6\u201d\uff0c\u5f53\u524d\u7684\u751f\u4ea7\u8fc7\u7a0b\u548c\u5236\u836f\u914d\u65b9\u662f\u4e00\u79cd\u201c\u827a\u672f\u201d\uff0c\u800c\u4e0d\u662f\u4e00\u95e8\u201c\u79d1\u5b66\u201d\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u836f\u54c1\u751f\u4ea7\u8d28\u91cf\u7684\u7ed3\u679c\u5982\u540c\u827a\u672f\u5448\u73b0\u90a3\u6837\uff0c\u76f8\u5f53\u4f9d\u8d56\u201c\u827a\u672f\u5bb6\u201d\u7684\u719f\u7ec3\u7a0b\u5ea6\u548c\u4e2a\u4eba\u7980\u8d4b\uff0c\u7ffb\u8bd1\u8fc7\u6765\u5c31\u662f\u201c\u8d28\u91cf\u975e\u5e38\u4e0d\u7a33\u5b9a\u3001\u4e00\u81f4\u6027\u975e\u5e38\u5dee\u201d\u3002\u5f88\u5c11\u6709\u4eba\u4f1a\u8ba4\u4e3a\uff0c\u5236\u836f\u8fc7\u7a0b\u80fd\u50cf\u82af\u7247\u751f\u4ea7\u90a3\u6837\uff0c\u5c06\u6bcf\u4e2a\u64cd\u4f5c\u89c4\u7a0b\u548c\u6b65\u9aa4\u8fdb\u884c\u5de5\u7a0b\u5316\u5206\u89e3\u4e0e\u6570\u5b57\u5316\u4f20\u9012\uff0c\u5f62\u6210\u53ef\u4ee5\u81ea\u5b66\u4e60\u7684\u6267\u884c\u6307\u4ee4\uff0c\u4fdd\u969c\u6bcf\u4e00\u6279\u4ea7\u54c1\u7684\u8d28\u91cf\u90fd\u5177\u6709\u4e00\u81f4\u6027\uff0c\u8fd9\u6837\u7ec8\u7aef\u7528\u6237\u6216\u4e34\u5e8a\u60a3\u8005\u53ef\u4ee5\u4e0d\u5fc5\u8d4c\u8fd0\u6c14\u5c31\u53ef\u4ee5\u83b7\u5f97\u8d28\u91cf\u597d\u7684\u7ec8\u4ea7\u54c1\u3002\u5c31\u50cf\u901a\u8fc7\u6570\u667a\u6280\u672f\uff0c\u6211\u4eec\u968f\u610f\u6253\u5f00\u5531\u7247\u673a\uff0c\u5c31\u80fd\u6b23\u8d4f\u5230\u5927\u5e08\u7ea7\u7684\u4f5c\u54c1\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n <\/section>\n

\n
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\n \n \n \n \n <\/path>\n <\/path>\n <\/g>\n <\/g>\n <\/svg>\n <\/section>\n
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\n \u6ce8\u89e3<\/span><\/span>\n <\/p>\n

\n \u2460 CAR-T\uff08Chimeric Antigen Receptor T-Cell Immunotherapy\uff09\u662f\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\u514d\u75ab\u7597\u6cd5\u7684\u82f1\u6587\u7b80\u79f0\uff0c\u662f\u6cbb\u7597\u80bf\u7624\u7684\u65b0\u578b\u7cbe\u51c6\u9776\u5411\u7597\u6cd5\u3002\u5728\u5b9e\u9a8c\u5ba4\uff0c\u6280\u672f\u4eba\u5458\u901a\u8fc7\u57fa\u56e0\u5de5\u7a0b\u6280\u672f\uff0c\u5c06T\u7ec6\u80de\u6fc0\u6d3b\uff0c\u5e76\u88c5\u4e0a\u5b9a\u4f4d\u5bfc\u822a\u88c5\u7f6eCAR(\u80bf\u7624\u5d4c\u5408\u6297\u539f\u53d7\u4f53)\uff0c\u5c06T\u7ec6\u80de\u8fd9\u4e2a\u666e\u901a\u201c\u6218\u58eb\u201d\u6539\u9020\u6210\u201c\u8d85\u7ea7\u6218\u58eb\u201d\uff0c\u5373CAR-T\u7ec6\u80de\uff0c\u5b83\u5229\u7528\u5176\u201c\u5b9a\u4f4d\u5bfc\u822a\u88c5\u7f6e\u201dCAR\uff0c\u4e13\u95e8\u8bc6\u522b\u4f53\u5185\u80bf\u7624\u7ec6\u80de\uff0c\u5e76\u901a\u8fc7\u514d\u75ab\u4f5c\u7528\u91ca\u653e\u5927\u91cf\u7684\u591a\u79cd\u6548\u5e94\u56e0\u5b50\uff0c\u5b83\u4eec\u80fd\u9ad8\u6548\u5730\u6740\u706d\u80bf\u7624\u7ec6\u80de\uff0c\u4ece\u800c\u8fbe\u5230\u6cbb\u7597\u6076\u6027\u80bf\u7624\u7684\u76ee\u7684\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u2461 TIL\uff08Tumor Infiltrating Lymphocytes\uff0c\u80bf\u7624\u6d78\u6da6\u6dcb\u5df4\u7ec6\u80de)\u7597\u6cd5\u662f\u6307\u4ece\u80bf\u7624\u7ec4\u7ec7\u4e2d\u5206\u79bb\u80bf\u7624\u6d78\u6da6\u7684\u6dcb\u5df4\u7ec6\u80de\uff0c\u5728\u4f53\u5916\u57f9\u517b\u548c\u5927\u91cf\u6269\u589e\u540e\u56de\u8f93\u5230\u75c5\u4eba\u4f53\u5185\u7684\u7597\u6cd5\u3002TIL\u7597\u6cd5\u7684\u6548\u5e94\u7ec6\u80de\u662f\u7ecf\u8fc7\u5929\u7136\u9009\u62e9\u4e0e\u5bcc\u96c6\uff0c\u80bf\u7624\u7279\u5f02\u6027T\u7ec6\u80de\u6bd4\u4f8b\u9ad8\u4e14\u591a\u6837\u6027\u4e30\u5bcc\u7684\u7fa4\u4f53\uff0c\u4e0eCAR-T\u7ec6\u80de\u7597\u6cd5\u548cPD-1\/PD-L1\u6297\u4f53\u76f8\u6bd4\uff0c\u5177\u6709\u591a\u9776\u70b9\u3001\u80bf\u7624\u8d8b\u5411\u548c\u6d78\u6da6\u80fd\u529b\u5f3a\u3001\u526f\u4f5c\u7528\u5c0f\u7b49\u4f18\u70b9\u3002<\/span>\n <\/p>\n

\n \u2462 \u683c\u5217\u536b\uff08\u901a\u7528\u540d\u7532\u78fa\u9178\u4f0a\u9a6c\u66ff\u5c3c\uff09\u662f\u745e\u58eb\u8bfa\u534e\u7814\u5236\u7684\u4e00\u7c7b\u9488\u5bf9\u767d\u8840\u75c5\u7684\u80bf\u7624\u9776\u5411\u836f\uff0c\u683c\u5217\u536b\u662f\u4e00\u79cd\u53e3\u670d\u7684\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\u7c7b\u836f\u7269\uff0c\u662f\u6cbb\u7597\u6162\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08CML\uff09\u7684\u4e00\u7ebf\u7528\u836f\uff0c\u80fd\u4f7fCML\u60a3\u8005\u768410\u5e74\u751f\u5b58\u7387\u8fbe85%~90%\uff0c\u5927\u5927\u5ef6\u957f\u4e86\u60a3\u8005\u7684\u751f\u547d\u5468\u671f\uff0c\u88ab\u8a89\u4e3a\u201c\u6162\u6027\u7c92\u7ec6\u80de\u767d\u8840\u75c5\u6551\u547d\u836f\u201d\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u2463 B+A\uff0cA\u7ea7\uff08\u9ad8\u98ce\u9669\u64cd\u4f5c\u533a\uff09\u901a\u5e38\u662f\u6307\u6d01\u51c0\u5ea6\u7b49\u7ea7B\u7ea7\u548cA\u7ea7\u7684\u7ed3\u5408\uff0c\u5176\u4e2d\uff0cB\u7ea7\u662f\u65e0\u83cc\u914d\u5236\u548c\u704c\u88c5\u7b49\u9ad8\u98ce\u9669\u64cd\u4f5cA\u7ea7\u6d01\u51c0\u533a\u6240\u5904\u7684\u80cc\u666f\u533a\u57df\uff0c\u800cA\u7ea7\u662f\u9ad8\u98ce\u9669\u64cd\u4f5c\u533a\uff0c\u5982\u704c\u88c5\u533a\u3001\u653e\u7f6e\u80f6\u585e\u6876\u548c\u4e0e\u65e0\u83cc\u5236\u5242\u76f4\u63a5\u63a5\u89e6\u7684\u655e\u53e3\u5305\u88c5\u5bb9\u5668\u7684\u533a\u57df\u53ca\u65e0\u83cc\u88c5\u914d\u6216\u8fde\u63a5\u64cd\u4f5c\u7684\u533a\u57df\u3002\u5177\u4f53\u6765\u8bf4\uff0cA\u7ea7\u6d01\u51c0\u533a\u5728\u52a8\u6001\u6761\u4ef6\u4e0b\u5e94\u4ecd\u4e3a\u767e\u7ea7\uff0c\u5373\u5728\u64cd\u4f5c\u8fc7\u7a0b\u4e2d\u7a7a\u6c14\u4e2d\u7684\u60ac\u6d6e\u7c92\u5b50\u6570\u5e94\u7b26\u5408\u767e\u7ea7\u6807\u51c6\uff0c\u800cB\u7ea7\u6d01\u51c0\u533a\u5728\u9759\u6001\u6761\u4ef6\u4e0b\u6ee1\u8db3\u767e\u7ea7\u6807\u51c6\uff0c\u5728\u52a8\u6001\u6761\u4ef6\u4e0b\u53ef\u4ee5\u7b26\u5408\u4e07\u7ea7\u6807\u51c6\u3002\u5728\u65b0\u7248GMP\u4e2d\uff0cA\u7ea7\u548cB\u7ea7\u6d01\u51c0\u533a\u7684\u7a7a\u6c14\u60ac\u6d6e\u7c92\u5b50\u7684\u6700\u5927\u5141\u8bb8\u6570\u6709\u660e\u786e\u7684\u6570\u503c\u89c4\u5b9a\uff0cA\u7ea7\u4e3a3520\u4e2a\/\u7acb\u65b9\u7c73\uff08\u22650.5\u5fae\u7c73\uff09\u548c20\u4e2a\/\u7acb\u65b9\u7c73\uff08\u22655\u5fae\u7c73\uff09\uff0cB\u7ea7\u9759\u6001\u4e3a3520\u4e2a\/\u7acb\u65b9\u7c73\uff08\u22650.5\u5fae\u7c73\uff09\u548c29\u4e2a\/\u7acb\u65b9\u7c73\uff08\u22655\u5fae\u7c73\uff09\uff0c\u52a8\u6001\u5219\u4e3a352000\u4e2a\/\u7acb\u65b9\u7c73\uff08\u22650.5\u5fae\u7c73\uff09\u548c2900\u4e2a\/\u7acb\u65b9\u7c73\uff08\u22655\u5fae\u7c73\uff09\u3002\u6d01\u51c0\u533a\u7b49\u7ea7B+A\u7684\u8bbe\u7f6e\u662f\u4e3a\u4e86\u786e\u4fdd\u836f\u54c1\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u7684\u65e0\u83cc\u73af\u5883\uff0c\u9632\u6b62\u5fae\u751f\u7269\u6c61\u67d3\uff0c\u4fdd\u969c\u836f\u54c1\u7684\u8d28\u91cf\u548c\u5b89\u5168\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u2464 rFib:\u81ea\u4f53\u7ec6\u80de\u5e74\u8f7b\u5316\uff0c\u5168\u7403\u72ec\u4e00\u65e0\u4e8c\u7684\u9886\u5148\u578b\u751f\u547d\u79d1\u6280\u4e13\u5229\u6280\u672f\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u2465 GMP\uff08Good Manufacturing Practice\uff09\uff1a\u826f\u597d\u751f\u4ea7\u89c4\u8303\uff0c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u5c06\u5176\u5b9a\u4e49\u4e3a\u6307\u5bfc\u98df\u7269\u3001\u836f\u54c1\u3001\u533b\u7597\u4ea7\u54c1\u751f\u4ea7\u548c\u8d28\u91cf\u7ba1\u7406\u7684\u6cd5\u89c4\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u2466 2018\u5e74\u4e16\u754c\u7ecf\u6d4e\u8bba\u575b\u65b0\u9886\u519b\u8005\u5e74\u4f1a\u3002<\/span>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n

\n

\n \n <\/p>\n

\n \u53c2 \u8003 \u6587 \u732e<\/span><\/strong><\/span>\n <\/p>\n <\/section>\n

\n \n <\/p>\n

\n [1] \u5f20\u747e. \u63d0\u9ad8CAR-T\u53ef\u53ca\u6027\u7684\u6d77\u5916\u7ecf\u9a8c[N\/OL]. \u4e2d\u56fd\u94f6\u884c\u4fdd\u9669\u62a5\uff0c2021-10-19(5). DOI: 10. 28049\/n. cnki. ncbxb. 2021. 003803. <\/span>\n <\/p>\n

\n [2] \u5d14\u7b11\u5929. \u201c\u767e\u4e07\u7ea7\u201d\u4ea7\u54c1\u5bfb\u627e\u521b\u65b0\u652f\u4ed8\u8def\u5f84[N\/OL]. \u534e\u590f\u65f6\u62a5\uff0c2021-09-13(8). DOI: 10. 28391\/n. cnki. nhxsb. 2021. 000792. <\/span>\n <\/p>\n

\n [3] \u6881\u6674\uff0c\u5f20\u6842\u6885\uff0c\u859b\u68a6\u4f1f. \u7531\u751f\u4ea7\u5316\u5b66\u836f\u5411\u751f\u7269\u836f\u8f6c\u53d8\u9c81\u6297\u533b\u836f\u4ee5\u6570\u667a\u5316\u8f6c\u578b\u53d1\u5c55\u65b0\u8d28\u751f\u4ea7\u529b[J]. \u5c71\u4e1c\u56fd\u8d44\uff0c2024(5): 18-19. <\/span>\n <\/p>\n

\n [4] \u5d14\u82b3\u83f2. \u970d\u5c3c\u97e6\u5c14\u8d4b\u80fd\u751f\u547d\u79d1\u5b66\u6570\u667a\u5316\u8f6c\u578b\uff0c\u5f00\u542f\u65b0\u8d28\u751f\u4ea7\u529b\u65b0\u7eaa\u5143[J]. \u6d41\u7a0b\u5de5\u4e1a\uff0c2024(6): 22-24. <\/span>\n <\/p>\n

\n [5] \u5434\u5dcd. \u4f9b\u5e94\u94fe\u63a7\u5236\u5854\u6784\u5efa\u533b\u836f\u4ea7\u4e1a\u667a\u80fd\u5316\u751f\u6001\u5708[J]. \u7269\u6d41\u6280\u672f\u4e0e\u5e94\u7528\uff0c2024\uff0c29(5): 160-165. <\/span>\n <\/p>\n

\n [6] \u201c\u706f\u5854\u5de5\u5382\u201d\u5f15\u9886\u5236\u9020\u4e1a\u6570\u5b57\u5316\u8f6c\u578b[J\/OL]. \u8f6f\u4ef6\u548c\u96c6\u6210\u7535\u8def\uff0c2021(11): 78-83. DOI: 10. 19609\/j. cnki. cn10-1339\/tn. 2021. 11. 021. <\/span>\n <\/p>\n <\/section>\n

\n

\n \n <\/p>\n

\n \u672c\u6587\u6458\u5f15\u81ea\u300a\u4e2d\u56fd\u5065\u5eb7\u7ecf\u6d4e\u8bc4\u8bba2024\u300b<\/span>\n <\/p>\n

\n <\/span>\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014<\/span>\n <\/p>\n <\/section>\n<\/section>\n

\n
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\n \u5f80\u671f\u7cbe\u9009\u4e00<\/strong><\/span>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n
\n
\n

\n 2021\u5e74\u20142024\u5e74<\/span>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n

\n
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\n
\n <\/section>\n <\/section>\n <\/section>\n
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\n \u70b9\u51fb\u67e5\u770b\u66f4\u591a>>\u6c90\u82b8\u89c2\u70b9<<<\/span><\/a>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n

\n
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\n \u5f80\u671f\u7cbe\u9009\u4e8c<\/strong><\/span>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n
\n
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\n 2019\u5e74\u2014\u20142020<\/span>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n

\n
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\n <\/section>\n <\/section>\n <\/section>\n
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\n \u6c90\u82b8\u89c2\u70b9(1)|\u8fd0\u52a8\u4f7f\u4eba\u5e74\u8f7b\u5417\uff1f<\/span><\/span><\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(2)|\u4ece\u795e\u7ecf\u751f\u7406\u5b66\u89d2\u5ea6\u770b\u516c\u5171\u536b\u751f\u51b3\u7b56\u96be\u9898\uff1a\u8682\u8681\u8fd8\u662f\u86b1\u8722\uff1f<\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(3)|\u7f8e\u56fd\u75ab\u60c5\u9632\u63a7\u7a97\u53e3\u9519\u5931\u7684\u542f\u53d1\uff1a \u7ba1\u7406\u4e2d\u7684\u9632\u5fae\u675c\u6e10<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(4)|ASCO2020\u5e74\u4f1a\u6982\u8981<\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(5)|\u6539\u53d8\u4e16\u754c\u7684\u751f\u7269\u9769\u547d<\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(6)|\u65b0\u51a0\u75c5\u6bd2\u662f\u5982\u4f55\u653b\u9677\u4eba\u4f53\u514d\u75ab\u7cfb\u7edf\u7684\uff1f<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(7)|\u5f53\u8d44\u6e90\u4e0d\u8db3\u65f6\uff0c\u53ef\u80fd\u7f3a\u7684\u4e0d\u662f\u8d44\u6e90\u672c\u8eab\uff0c\u800c\u662f\u601d\u8def<\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(8)| \u7ec6\u80de\u4ea7\u4e1a\u65b0\u57fa\u5efa\u2014\u2014\u201c1\u5e931\u4e2d\u5fc31\u5e73\u53f0\u201d\u56fd\u5bb6\u7f51\u7edc<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(9)|COVID-19\u6311\u6218\u7684\u662f\u514d\u75ab\u529b \u662f\u5426\u201c\u53ec\u80fd\u6218\u3001\u6218\u5fc5\u80dc\u201d<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(10)|\u7f8e\u56fd\u516c\u5171\u536b\u751f\u670d\u52a1\u90e8\u961f\u4ecb\u7ecd<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(11)|<\/span>\u5982\u4f55\u7528\u5927\u89c4\u6a21\u6807\u51c6\u5316\u6d41\u7a0b\u5b9e\u73b0\u4e2a\u4f53\u5316\u6cbb\u7597<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(12)<\/span>| \u75ab\u60c5\u542f\u793a\uff1a\u4e0b\u6b21\u75ab\u60c5\uff0c\u6211\u4eec\u5982\u4f55\u5e94\u5bf9\uff1f<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(13)<\/span>| \u603b\u4e66\u8bb0\u70b9\u540d\u7684\u5e72\u7ec6\u80de\u5982\u4f55\u7528\u4e8e\u65b0\u51a0\u80ba\u708e\u6cbb\u7597\uff1f<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(14)<\/span>| \u7d27\u6025\u72b6\u6001\u4e0b\uff0c\u4f53\u6064\u6cbb\u7597\u7684\u524d\u63d0\u6761\u4ef6\u662f\u4ec0\u4e48\uff1f<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(15)<\/span>| WHO\u8ba4\u4e3a\u65b0\u51a0\u75ab\u60c5\u8fd8\u4e0d\u7b26\u5408\u5927\u6d41\u884c\u201c\u8513\u5ef6\u56fd\u754c\u201d\u7684\u7279\u5f81<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(16)<\/span>| \u4ece\u9996\u4f8b\u65b0\u51a0\u60a3\u8005\u4e2a\u6848\u770b\u7f8e\u56fd\u75ab\u60c5\u9632\u63a7\u542f\u52a8\u673a\u5236<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(17)<\/span>| \u5173\u4e8e\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u7684\u4ecb\u7ecd<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(18)<\/span>| 2019\u5e74\u2014\u2014\u56fd\u9645\u518d\u751f\u533b\u5b66\u4ea7\u4e1a\u5e74<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(19)<\/span>| \u65e5\u672c\u5c0f\u8bb0<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9<\/span>(20)<\/span>| \u751f\u7269\u6837\u672c\u5e93\u5728\u5987\u5e7c\u5065\u5eb7\u9886\u57df\u7684\u5e94\u7528\u5c55\u671b<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(21)| \u5218\u6c90\u82b8\uff1a\u7b2c\u4e09\u65b9\u7ec6\u80de\u8d28\u91cf\u68c0\u6d4b\u5e73\u53f0\u7684\u804c\u80fd\u548c\u80fd\u529b<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(22)| \u529f\u6210\u4e0d\u5fc5\u5728\u6211\uff0c\u529f\u6210\u5fc5\u5b9a\u6709\u6211<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(23)| \u5218\u6c90\u82b8\uff1a\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u2014\u2014\u6df1\u5733\u7684\u673a\u9047\u4e0e\u6311\u6218<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(24)| \u8bfa\u8d1d\u5c14\u5956\u7684\u6210\u679c\u8f6c\u5316<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(25)| \u5218\u6c90\u82b8\uff1a\u5e72\u7ec6\u80de\u4e34\u5e8a\u7814\u7a76\u4e2d\u4f01\u4e1a\u7684\u673a\u9047\u4e0e\u8d23\u4efb<\/span><\/a>\n <\/p>\n

\n \u6c90\u82b8\u89c2\u70b9(26)| 5\u95ee\u533b\u5b66\u4eba\u5de5\u667a\u80fd\uff0c\u662f\u5426\u5728\u201c\u88f8\u6cf3\u201d\uff1f<\/span><\/a>\n <\/p>\n

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